Meropenem-induced Valproic Acid Elimination: A Case Report of Clinically Relevant Drug Interaction

We present two case reports of drug interaction between valproic acid and meropenem. In comparison with expected population-kinetic based serum levels, we observed 90.8 and 93.5% decrease in valproic acid serum levels during concomitant administration with meropenem. If carbapenems need to be admini...

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Bibliographic Details
Main Authors: Martin Šíma, Jan Hartinger, Jan Rulíšek, Robert Šachl, Ondřej Slanař
Format: Article
Language:English
Published: Karolinum Press 2017-09-01
Series:Prague Medical Report
Subjects:
Online Access:https://pmr.lf1.cuni.cz/118/2/0105/