Structural insights into phenylethanolamines high-affinity binding site in NR2B from binding and molecular modeling studies
<p>Abstract</p> <p>Background</p> <p>Phenylethanolamines selectively bind to NR2B subunit-containing <it>N</it>-methyl-<it>D</it>-aspartate-subtype of ionotropic glutamate receptors and negatively modulate receptor activity. To investigate the st...
Main Authors: | , , , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2008-11-01
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Series: | Molecular Brain |
Online Access: | http://www.molecularbrain.com/content/1/1/16 |