Structural insights into phenylethanolamines high-affinity binding site in NR2B from binding and molecular modeling studies

<p>Abstract</p> <p>Background</p> <p>Phenylethanolamines selectively bind to NR2B subunit-containing <it>N</it>-methyl-<it>D</it>-aspartate-subtype of ionotropic glutamate receptors and negatively modulate receptor activity. To investigate the st...

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Bibliographic Details
Main Authors: Ng Fui-Mee, Geballe Matthew T, Snyder James P, Traynelis Stephen F, Low Chian-Ming
Format: Article
Language:English
Published: BMC 2008-11-01
Series:Molecular Brain
Online Access:http://www.molecularbrain.com/content/1/1/16