DEAD-box RNA helicase Dbp4/DDX10 is an enhancer of α-synuclein toxicity and oligomerization.

DEAD-box RNA helicase Dbp4/DDX10 is an enhancer of α-synuclein toxicity and oligomerization.

Parkinson's disease is a neurodegenerative disorder associated with misfolding and aggregation of α-synuclein as a hallmark protein. Two yeast strain collections comprising conditional alleles of essential genes were screened for the ability of each allele to reduce or improve yeast growth upon...

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Bibliographic Details
Main Authors: Blagovesta Popova, Dan Wang, Christina Pätz, Dagmar Akkermann, Diana F Lázaro, Dajana Galka, Miriam Kolog Gulko, Markus T Bohnsack, Wiebke Möbius, Katherine E Bohnsack, Tiago F Outeiro, Gerhard H Braus
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-03-01
Series:PLoS Genetics
Online Access:https://doi.org/10.1371/journal.pgen.1009407

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https://doi.org/10.1371/journal.pgen.1009407

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