Dual mechanism design to enhance bone formation by overexpressed SDF-1 ADSCs in magnesium doped calcium phosphate scaffolds

Background: SDF-1/CXCR4 axis plays a critical role in the mobilization and regeneration of host-derived cells. Little is known around the role of SDF-1 gene on bone regeneration. This study was conceptualized to create a 2-in-1 strategy by identifying potential role of SDF-1 on promoting endogenous...

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Bibliographic Details
Main Authors: Zhaoqi Sun, Chao Lin, Kailiu Wu, Mingyi Wang
Format: Article
Language:English
Published: Elsevier 2021-10-01
Series:Materials & Design
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0264127521004378