PPAR-Responsive Elements Enriched with Alu Repeats May Contribute to Distinctive PPARγ–DNMT1 Interactions in the Genome

PPAR-Responsive Elements Enriched with Alu Repeats May Contribute to Distinctive PPARγ–DNMT1 Interactions in the Genome

Background: PPARγ (peroxisome proliferator-activated receptor gamma) is involved in the pathology of numerous diseases, including UM and other types of cancer. Emerging evidence suggests that an interaction between PPARγ and DNMTs (DNA methyltransferase) plays a role in cancer that is yet to be defi...

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Bibliographic Details
Main Authors: Amit Sharma, Fabian Tobar-Tosse, Tikam Chand Dakal, Hongde Liu, Arijit Biswas, Athira Menon, Anoosha Paruchuri, Panagiotis Katsonis, Olivier Lichtarge, M. Michael Gromiha, Michael Ludwig, Ingo G. H. Schmidt-Wolf, Frank G. Holz, Karin U. Loeffler, Martina C. Herwig-Carl
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Cancers
Subjects:
cancer
repetitive sequences
evolutionary action score
uveal melanoma
Alu repeats
PPARγ
Online Access:https://www.mdpi.com/2072-6694/13/16/3993

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https://www.mdpi.com/2072-6694/13/16/3993

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