CSF T-Tau/Aβ42 predicts white matter microstructure in healthy adults at risk for Alzheimer's disease.

Cerebrospinal fluid (CSF) biomarkers T-Tau and Aβ(42) are linked with Alzheimer's disease (AD), yet little is known about the relationship between CSF biomarkers and structural brain alteration in healthy adults. In this study we examined the extent to which AD biomarkers measured in CSF predic...

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Bibliographic Details
Main Authors: Barbara B Bendlin, Cynthia M Carlsson, Sterling C Johnson, Henrik Zetterberg, Kaj Blennow, Auriel A Willette, Ozioma C Okonkwo, Aparna Sodhi, Michele L Ries, Alex C Birdsill, Andrew L Alexander, Howard A Rowley, Luigi Puglielli, Sanjay Asthana, Mark A Sager
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22701578/pdf/?tool=EBI