In vivo notch signaling blockade induces abnormal spermatogenesis in the mouse.

In a previous study we identified active Notch signaling in key cellular events occurring at adult spermatogenesis. In this study, we evaluated the function of Notch signaling in spermatogenesis through the effects of in vivo Notch blockade. Adult CD1 male mice were either submitted to a long term D...

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Bibliographic Details
Main Authors: Daniel Murta, Marta Batista, Alexandre Trindade, Elisabete Silva, Domingos Henrique, António Duarte, Luís Lopes-da-Costa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4239051?pdf=render