Stress Response Leading to Resistance in Glioblastoma—The Need for Innovative Radiotherapy (iRT) Concepts

Glioblastoma (GBM) is the most common and most aggressive malignant primary brain tumor in adults. In spite of multimodal therapy concepts, consisting of surgery, radiotherapy and chemotherapy, the median survival, merely 15–18 months, is still poor. Mechanisms for resistance of GBM to radio(chemo)t...

Full description

Bibliographic Details
Main Authors: Stephanie E. Combs, Thomas E. Schmid, Peter Vaupel, Gabriele Multhoff
Format: Article
Language:English
Published: MDPI AG 2016-01-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/8/1/15