Vincristine-Induced Peripheral Neuropathy (VIPN) in Pediatric Tumors: Mechanisms, Risk Factors, Strategies of Prevention and Treatment

Vincristine-Induced Peripheral Neuropathy (VIPN) in Pediatric Tumors: Mechanisms, Risk Factors, Strategies of Prevention and Treatment

Vincristine-induced peripheral neurotoxicity (VIPN) is a very common side effect of vincristine chemotherapy among pediatric patients with cancer. Neuropathy may be sensory, motor and/or autonomic, with consequent reduction, delay or discontinuation of vincristine-chemotherapy, but also pain, disabi...

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Bibliographic Details
Main Authors: Silvia Triarico, Alberto Romano, Giorgio Attinà, Michele Antonio Capozza, Palma Maurizi, Stefano Mastrangelo, Antonio Ruggiero
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
vincristine
chemotherapy-induced peripheral neuropathy
pediatric cancer
molecular mechanisms
risk factors
prevention
Online Access:https://www.mdpi.com/1422-0067/22/8/4112

Internet

https://www.mdpi.com/1422-0067/22/8/4112

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