Comparative pathway and network analysis of brain transcriptome changes during adult aging and in Parkinson's disease

Aging is considered as one of the main factors promoting the risk for Parkinson's disease (PD), and common mechanisms of dopamine neuron degeneration in aging and PD have been proposed in recent years. Here, we use a statistical meta-analysis of human brain transcriptomics data to investigate p...

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Bibliographic Details
Main Authors: Enrico Glaab, Reinhard Schneider
Format: Article
Language:English
Published: Elsevier 2015-02-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996114003404