Disparity between Inter-Patient Molecular Heterogeneity and Repertoires of Target Drugs Used for Different Types of Cancer in Clinical Oncology

Disparity between Inter-Patient Molecular Heterogeneity and Repertoires of Target Drugs Used for Different Types of Cancer in Clinical Oncology

Inter-patient molecular heterogeneity is the major declared driver of an expanding variety of anticancer drugs and personalizing their prescriptions. Here, we compared interpatient molecular heterogeneities of tumors and repertoires of drugs or their molecular targets currently in use in clinical on...

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Bibliographic Details
Main Authors: Marianna A. Zolotovskaia, Maxim I. Sorokin, Ivan V. Petrov, Elena V. Poddubskaya, Alexey A. Moiseev, Marina I. Sekacheva, Nicolas M. Borisov, Victor S. Tkachev, Andrew V. Garazha, Andrey D. Kaprin, Peter V. Shegay, Alf Giese, Ella Kim, Sergey A. Roumiantsev, Anton A. Buzdin
Format: Article
Language:English
Published: MDPI AG 2020-02-01
Series:International Journal of Molecular Sciences
Subjects:
clinical oncology
targeted therapeutics
cancer drugs
chemotherapy
molecular diagnostics
mutations
genome
transcriptome
tumor heterogeneity
personalized medicine
Online Access:https://www.mdpi.com/1422-0067/21/5/1580

Internet

https://www.mdpi.com/1422-0067/21/5/1580

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