Impact of prophylactic TNF blockade in the dual PD-1 and CTLA-4 immunotherapy efficacy and toxicity

Impact of prophylactic TNF blockade in the dual PD-1 and CTLA-4 immunotherapy efficacy and toxicity

The TNF blockade therapy is currently a well-established treatment option for a variety of autoimmune diseases such as rheumatoid arthritis (RA), psoriasis or Crohn’s disease, given the proinflammatory role of TNF in the course of these diseases. Importantly, TNF neutralization is also used for the...

Full description

Bibliographic Details
Main Authors: Maite Alvarez, Itziar Otano, Luna Minute, Maria Carmen Ochoa, Elisabeth Perez-Ruiz, Ignacio Melero, Pedro Berraondo
Format: Article
Language:English
Published: Shared Science Publishers OG 2019-06-01
Series:Cell Stress
Subjects:
CTLA-4
PD-1
immunotherapy
cancer
tumor necrosis factor
toxicity
colitis
Online Access:http://www.cell-stress.com/researcharticles/2019a-alvarez-cell-stress/

Internet

http://www.cell-stress.com/researcharticles/2019a-alvarez-cell-stress/

Similar Items