Small-Molecule Control of Super-Mendelian Inheritance in Gene Drives

Small-Molecule Control of Super-Mendelian Inheritance in Gene Drives

Summary: Synthetic CRISPR-based gene-drive systems have tremendous potential in public health and agriculture, such as for fighting vector-borne diseases or suppressing crop pest populations. These elements can rapidly spread in a population by breaching the inheritance limit of 50% dictated by Mend...

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Bibliographic Details
Main Authors: Víctor López Del Amo, Brittany S. Leger, Kurt J. Cox, Shubhroz Gill, Alena L. Bishop, Garrett D. Scanlon, James A. Walker, Valentino M. Gantz, Amit Choudhary
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Cell Reports
Subjects:
gene drive
split gene drive
CopyCat
super-Mendelian
small molecule
drug control
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124720308226

Internet

http://www.sciencedirect.com/science/article/pii/S2211124720308226

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