Ganoderma Lucidum Polysaccharide Peptide Alleviates Hepatoteatosis via Modulating Bile Acid Metabolism Dependent on FXR-SHP/FGF

Ganoderma Lucidum Polysaccharide Peptide Alleviates Hepatoteatosis via Modulating Bile Acid Metabolism Dependent on FXR-SHP/FGF

Background/Aims: Non-alcoholic fatty liver disease (NAFLD) encompasses a series of pathologic changes ranging from steatosis to steatohepatitis, which may progress to cirrhosis and hepatocellular carcinoma. The purpose of this study was to determine whether ganoderma lucidum polysaccharide peptide (...

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Bibliographic Details
Main Authors: Dandan Zhong, Zhengwei Xie, Boyue Huang, Shuai Zhu, Guoqian Wang, Hong Zhou, Shuqian Lin, Zhibin Lin, Baoxue Yang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
Ganoderma lucidum polysaccharide peptide
NAFLD
Insulin resistance
hepatosteatosis
Metabolomics
Bile acid synthesis
Nuclear receptors
Fatty acid synthesis
Online Access:https://www.karger.com/Article/FullText/493297

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https://www.karger.com/Article/FullText/493297

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