Genetic Variability Overrides the Impact of Parental Cell Type and Determines iPSC Differentiation Potential

Genetic Variability Overrides the Impact of Parental Cell Type and Determines iPSC Differentiation Potential

Reports on the retention of somatic cell memory in induced pluripotent stem cells (iPSCs) have complicated the selection of the optimal cell type for the generation of iPSC biobanks. To address this issue we compared transcriptomic, epigenetic, and differentiation propensities of genetically matched...

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Bibliographic Details
Main Authors: Aija Kyttälä, Roksana Moraghebi, Cristina Valensisi, Johannes Kettunen, Colin Andrus, Kalyan Kumar Pasumarthy, Mahito Nakanishi, Ken Nishimura, Manami Ohtaka, Jere Weltner, Ben Van Handel, Olavi Parkkonen, Juha Sinisalo, Anu Jalanko, R. David Hawkins, Niels-Bjarne Woods, Timo Otonkoski, Ras Trokovic
Format: Article
Language:English
Published: Elsevier 2016-02-01
Series:Stem Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2213671115003744

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http://www.sciencedirect.com/science/article/pii/S2213671115003744

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