Targeting a highly repeated germline DNA sequence for improved real-time PCR-based detection of Ascaris infection in human stool.

<h4>Background</h4>With the expansion of soil transmitted helminth (STH) intervention efforts and the corresponding decline in infection prevalence, there is an increased need for sensitive and specific STH diagnostic assays. Previously, through next generation sequencing (NGS)-based ide...

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Bibliographic Details
Main Authors: Nils Pilotte, Jacqueline R M A Maasch, Alice V Easton, Eric Dahlstrom, Thomas B Nutman, Steven A Williams
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-07-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0007593