Relationship between malaria incidence and IgG levels to Plasmodium falciparum merozoite antigens in Malian children: impact of hemoglobins S and C.

Heterozygous hemoglobin (Hb) AS (sickle-cell trait) and HbAC are hypothesized to protect against Plasmodium falciparum malaria in part by enhancing naturally-acquired immunity to this disease. To investigate this hypothesis, we compared antibody levels to four merozoite antigens from the P. falcipar...

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Bibliographic Details
Main Authors: Kazutoyo Miura, Mahamadou Diakite, Ababacar Diouf, Saibou Doumbia, Drissa Konate, Abdoul S Keita, Samuel E Moretz, Gregory Tullo, Hong Zhou, Tatiana M Lopera-Mesa, Jennifer M Anderson, Rick M Fairhurst, Carole A Long
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3610890?pdf=render