Folate-Equipped Cationic Liposomes Deliver Anti-MDR1-siRNA to the Tumor and Increase the Efficiency of Chemotherapy

Folate-Equipped Cationic Liposomes Deliver Anti-MDR1-siRNA to the Tumor and Increase the Efficiency of Chemotherapy

In this study, we examined the in vivo toxicity of the liposomes F consisting of 1,26-bis(cholest-5-en-3-yloxycarbonylamino)-7,11,16,20-tetraazahexacosan tetrahydrochloride, lipid-helper 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine and folate lipoconjugate (<i>O</i>-{2-[<i>rac<...

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Bibliographic Details
Main Authors: Daniil V. Gladkikh, Aleksandra V. Sen′kova, Ivan V. Chernikov, Tatyana O. Kabilova, Nelly A. Popova, Valery P. Nikolin, Elena V. Shmendel, Mikhail A. Maslov, Valentin V. Vlassov, Marina A. Zenkova, Elena L. Chernolovskaya
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Pharmaceutics
Subjects:
cationic liposomes
folate-containing lipoconjugate
folic acid
transfection
targeted delivery
siRNA
Online Access:https://www.mdpi.com/1999-4923/13/8/1252

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https://www.mdpi.com/1999-4923/13/8/1252

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