Chromatin-Remodelling Complex NURF Is Essential for Differentiation of Adult Melanocyte Stem Cells.

Chromatin-Remodelling Complex NURF Is Essential for Differentiation of Adult Melanocyte Stem Cells.

MIcrophthalmia-associated Transcription Factor (MITF) regulates melanocyte and melanoma physiology. We show that MITF associates the NURF chromatin-remodelling factor in melanoma cells. ShRNA-mediated silencing of the NURF subunit BPTF revealed its essential role in several melanoma cell lines and i...

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Bibliographic Details
Main Authors: Dana Koludrovic, Patrick Laurette, Thomas Strub, Céline Keime, Madeleine Le Coz, Sebastien Coassolo, Gabrielle Mengus, Lionel Larue, Irwin Davidson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4595011?pdf=render

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http://europepmc.org/articles/PMC4595011?pdf=render

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