Chromatin-Remodelling Complex NURF Is Essential for Differentiation of Adult Melanocyte Stem Cells.
MIcrophthalmia-associated Transcription Factor (MITF) regulates melanocyte and melanoma physiology. We show that MITF associates the NURF chromatin-remodelling factor in melanoma cells. ShRNA-mediated silencing of the NURF subunit BPTF revealed its essential role in several melanoma cell lines and i...
Main Authors: | Dana Koludrovic, Patrick Laurette, Thomas Strub, Céline Keime, Madeleine Le Coz, Sebastien Coassolo, Gabrielle Mengus, Lionel Larue, Irwin Davidson |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-10-01
|
Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC4595011?pdf=render |
Similar Items
-
Le rôle du complexe de remodelage de la chromatine NURF dans les mélanocytes et les mélanomes
by: Koludrovic, Dana
Published: (2014) -
Analysis of chromatin targeting modules in the chromatin remodelling enzyme NURF
by: Jang, Boyun
Published: (2014) -
Transcription factor MITF and remodeller BRG1 define chromatin organisation at regulatory elements in melanoma cells
by: Patrick Laurette, et al.
Published: (2015-03-01) -
Alternative splicing of NURF301 generates distinct NURF chromatin remodeling complexes with altered modified histone binding specificities.
by: So Yeon Kwon, et al.
Published: (2009-07-01) -
Genome-Wide Mapping Targets of the Metazoan Chromatin Remodeling Factor NURF Reveals Nucleosome Remodeling at Enhancers, Core Promoters and Gene Insulators.
by: So Yeon Kwon, et al.
Published: (2016-04-01)