Iodine(III) promotes cross-dehydrogenative coupling of N-hydroxyphthalimide and unactivated C(sp3)–H bonds

Robust and selective C–H functionalisation of alkanes remains a challenge. Here, iodine(III) mediates the radical coupling of N-hydroxyphthalimide and unactivated C(sp3)–H bonds in a range of cyclic and acyclic alkanes.

Bibliographic Details
Main Authors: Fufang Wu, Xuanzhen Han, Xuejian Li, Xiaobao Shen, Chang Wang, Zhimei Tian, Bin Cheng, Jingbin Zhang, Liangquan Sheng, Hongbin Zhai
Format: Article
Language:English
Published: Nature Publishing Group 2021-03-01
Series:Communications Chemistry
Online Access:https://doi.org/10.1038/s42004-021-00480-8