Ablating adult neurogenesis in the rat has no effect on spatial processing: evidence from a novel pharmacogenetic model.

The function of adult neurogenesis in the rodent brain remains unclear. Ablation of adult born neurons has yielded conflicting results about emotional and cognitive impairments. One hypothesis is that adult neurogenesis in the hippocampus enables spatial pattern separation, allowing animals to disti...

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Bibliographic Details
Main Authors: James O Groves, Isla Leslie, Guo-Jen Huang, Stephen B McHugh, Amy Taylor, Richard Mott, Marcus Munafò, David M Bannerman, Jonathan Flint
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS Genetics
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24039591/pdf/?tool=EBI