Oral delivery of exenatide-loaded hybrid zein nanoparticles for stable blood glucose control and β-cell repair of type 2 diabetes mice

Oral delivery of exenatide-loaded hybrid zein nanoparticles for stable blood glucose control and β-cell repair of type 2 diabetes mice

Abstract Background Exenatide is an insulinotropic peptide drug for type 2 diabetes treatment with low risk of hypoglycemia, and is administrated by subcutaneous injection. Oral administration is the most preferred route for lifelong treatment of diabetes, but oral delivery of peptide drug remains a...

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Bibliographic Details
Main Authors: Xiaoyan Bao, Kang Qian, Ping Yao
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Journal of Nanobiotechnology
Subjects:
Diabetes
Exenatide
Nanoparticle
Absorption enhancer
Oral delivery
Zein
Online Access:http://link.springer.com/article/10.1186/s12951-020-00619-0

Internet

http://link.springer.com/article/10.1186/s12951-020-00619-0

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