Distinct α-Synuclein strains and implications for heterogeneity among α-Synucleinopathies
The deposition of misfolded β-sheet enriched amyloid protein is a shared feature of many neurodegenerative diseases. Recent studies demonstrated the existence of conformationally diverse strains as a common property for multiple amyloidogenic proteins including α-Synuclein (α-Syn). α-Syn is misfolde...
Main Authors: | Chao Peng, Ronald J. Gathagan, Virginia M.-Y. Lee |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2018-01-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996117301705 |
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