Effect of Whole Tissue Culture and Basic Fibroblast Growth Factor on Maintenance of Tie2 Molecule Expression in Human Nucleus Pulposus Cells

Effect of Whole Tissue Culture and Basic Fibroblast Growth Factor on Maintenance of Tie2 Molecule Expression in Human Nucleus Pulposus Cells

Previous work showed a link between Tie2<sup>+</sup> nucleus pulposus progenitor cells (NPPC) and disc degeneration. However, NPPC remain difficult to maintain in culture. Here, we report whole tissue culture (WTC) combined with fibroblast growth factor 2 (FGF2) and chimeric FGF (cFGF) s...

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Bibliographic Details
Main Authors: Kosuke Sako, Daisuke Sakai, Yoshihiko Nakamura, Jordy Schol, Erika Matsushita, Takayuki Warita, Natsumi Horikita, Masato Sato, Masahiko Watanabe
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:International Journal of Molecular Sciences
Subjects:
intervertebral disc
nucleus pulposus
nucleus pulposus progenitor cell
Tie2 receptor
basic fibroblast growth factor
chimera fibroblast growth factor
Online Access:https://www.mdpi.com/1422-0067/22/9/4723

Internet

https://www.mdpi.com/1422-0067/22/9/4723

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