Investigating the effects of IDO1, PTGS2, and TGF-β1 overexpression on immunomodulatory properties of hTERT-MSCs and their extracellular vesicles

Investigating the effects of IDO1, PTGS2, and TGF-β1 overexpression on immunomodulatory properties of hTERT-MSCs and their extracellular vesicles

Abstract The therapeutic potential of mesenchymal stem cells (MSCs) is out of the question. Yet, recent drawbacks have resulted in a strategic shift towards the application of MSC-derived cell-free products such as extracellular vesicles (EVs). Recent reports revealed that functional properties of M...

Full description

Bibliographic Details
Main Authors: Azadeh Haghighitalab, Maryam M. Matin, Ahmad Amin, Shima Minaee, Hamid Reza Bidkhori, Thorsten R. Doeppner, Ahmad Reza Bahrami
Format: Article
Language:English
Published: Nature Publishing Group 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-87153-7

Internet

https://doi.org/10.1038/s41598-021-87153-7

Similar Items