Histone deacetylase inhibitors induce expression of chromosomally tagged variant-specific surface protein genes in Giardia lamblia

Histone deacetylase inhibitors induce expression of chromosomally tagged variant-specific surface protein genes in Giardia lamblia

Abstract Objective RNA interference and miRNA mediated mechanisms have been proposed to explain the expression of a specific variant of VSP at a time on the surface of Giardia lamblia. Recently, epigenetic mechanisms involving histone acetylations have been proposed to explain the process of vsp gen...

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Bibliographic Details
Main Authors: Daniel Roberto Orozco, Srinivas Garlapati
Format: Article
Language:English
Published: BMC 2020-03-01
Series:BMC Research Notes
Subjects:
Giardia lamblia
Variant specific surface protein
Endogenous tagging
Histone deacetylase inhibitors
Antigenic variation
Online Access:http://link.springer.com/article/10.1186/s13104-020-04995-6

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http://link.springer.com/article/10.1186/s13104-020-04995-6

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