New Potential Targets of Glucagon-Like Peptide 1 Receptor Agonists in Pancreatic β-Cells and Hepatocytes

It is well known that both insulin resistance and decreased insulin secretory capacity are important factors in the pathogenesis of type 2 diabetes mellitus (T2DM). In addition to genetic factors, obesity and lipotoxicity can increase the risk of T2DM. Glucagon-like peptide 1 (GLP-1) receptor agonis...

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Bibliographic Details
Main Author: Won-Young Lee
Format: Article
Language:English
Published: Academya Publishing Co. 2017-02-01
Series:Endocrinology and Metabolism
Subjects:
Online Access:https://e-enm.org/Synapse/Data/PDFData/2008ENM/enm-32-1.pdf