AeMOPE-1, a Novel Salivary Peptide From Aedes aegypti, Selectively Modulates Activation of Murine Macrophages and Ameliorates Experimental Colitis

AeMOPE-1, a Novel Salivary Peptide From Aedes aegypti, Selectively Modulates Activation of Murine Macrophages and Ameliorates Experimental Colitis

The sialotranscriptomes of Aedes aegypti revealed a transcript overexpressed in female salivary glands that codes a mature 7.8 kDa peptide. The peptide, specific to the Aedes genus, has a unique sequence, presents a putative secretory nature and its function is unknown. Here, we confirmed that the p...

Full description

Bibliographic Details
Main Authors: Priscila G. Lara, Eliane Esteves, Helioswilton Sales-Campos, Josiane B. Assis, Maressa O. Henrique, Michele S. Barros, Leila S. Neto, Pedro I. Silva, Joilson O. Martins, Cristina R. B. Cardoso, José M. C. Ribeiro, Anderson Sá-Nunes
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Immunology
Subjects:
Aedes aegypti
AeMOPE-1
macrophages
immunomodulation
experimental colitis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.681671/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.681671/full

Similar Items