Glioblastoma therapy with cytotoxic mesenchymal stromal cells optimized by bioluminescence imaging of tumor and therapeutic cell response.

Glioblastoma therapy with cytotoxic mesenchymal stromal cells optimized by bioluminescence imaging of tumor and therapeutic cell response.

Genetically modified adipose tissue derived mesenchymal stromal cells (hAMSCs) with tumor homing capacity have been proposed for localized therapy of chemo- and radiotherapy resistant glioblastomas. We demonstrate an effective procedure to optimize glioblastoma therapy based on the use of geneticall...

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Bibliographic Details
Main Authors: Maria Alieva, Juli R Bagó, Elisabet Aguilar, Carolina Soler-Botija, Olaia F Vila, Joan Molet, Sanjiv S Gambhir, Nuria Rubio, Jerónimo Blanco
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3328467?pdf=render

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http://europepmc.org/articles/PMC3328467?pdf=render

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