Deletion of the Mir-106b~ 25 MicroRNA cluster attenuates atherosclerosis in Apolipoprotein E knockout mice

Abstract Background MicroRNAs are short non-coding RNAs that regulate gene expression. The aim of this study was to gain an understanding of the possible role of the miR-106b~ 25 microRNA cluster in regulating atherosclerosis in mice. Methods MiR-106b~ 25 knockout mice were outcrossed into Apolipopr...

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Bibliographic Details
Main Authors: Jonathan Semo, Gil Chernin, Michael Jonas, Sara Shimoni, Jacob George
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Lipids in Health and Disease
Subjects:
Online Access:https://doi.org/10.1186/s12944-019-1155-8