Turnover of protein phosphorylation evolving under stabilizing selection

Turnover of protein phosphorylation evolving under stabilizing selection

Most proteins are regulated by posttranslational modifications and changes in these modifications contribute to evolutionary changes as well as to human diseases. Phosphorylation of serines, threonines and tyrosines are the most common modifications identified to date in eukaryotic proteomes. While...

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Bibliographic Details
Main Authors: Christian R Landry, Luca eFreschi, Taraneh eZarin, Alan eMoses
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Genetics
Subjects:
Protein phosphorylation
Evolution, Molecular
Stabilizing selection
phorphorylation cluster
protein regulation
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00245/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2014.00245/full

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