Plectasin, First Animal Toxin-Like Fungal Defensin Blocking Potassium Channels through Recognizing Channel Pore Region

Plectasin, First Animal Toxin-Like Fungal Defensin Blocking Potassium Channels through Recognizing Channel Pore Region

The potassium channels were recently found to be inhibited by animal toxin-like human β-defensin 2 (hBD2), the first defensin blocker of potassium channels. Whether there are other defensin blockers from different organisms remains an open question. Here, we reported the potassium channel-blocking p...

Full description

Bibliographic Details
Main Authors: Fang Xiang, Zili Xie, Jing Feng, Weishan Yang, Zhijian Cao, Wenxin Li, Zongyun Chen, Yingliang Wu
Format: Article
Language:English
Published: MDPI AG 2015-01-01
Series:Toxins
Subjects:
plectasin
defensin
potassium channels
Kv1.3 channel
molecular mechanism
functional evolution
Online Access:http://www.mdpi.com/2072-6651/7/1/34

Internet

http://www.mdpi.com/2072-6651/7/1/34

Similar Items