Circulating tumor DNA analysis depicts subclonal architecture and genomic evolution of small cell lung cancer
Small cell lung cancer (SCLC) may evolve under treatment. But tumor tissues are often not available to study evolution of SCLC. Here, the authors utilize circulating tumor DNA to investigate the genomic evolution and subclonal architecture of SCLC during therapy.
Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-08-01
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Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-05327-w |