Ca2+ signaling driving pacemaker activity in submucosal interstitial cells of Cajal in the murine colon

Ca2+ signaling driving pacemaker activity in submucosal interstitial cells of Cajal in the murine colon

Interstitial cells of Cajal (ICC) generate pacemaker activity responsible for phasic contractions in colonic segmentation and peristalsis. ICC along the submucosal border (ICC-SM) contribute to mixing and more complex patterns of colonic motility. We show the complex patterns of Ca2+ signaling in IC...

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Bibliographic Details
Main Authors: Salah A Baker, Wesley A Leigh, Guillermo Del Valle, Inigo F De Yturriaga, Sean M Ward, Caroline A Cobine, Bernard T Drumm, Kenton M Sanders
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2021-01-01
Series:eLife
Subjects:
pacemaker
slow waves
ca2+ entry
ca2+-induced ca2+ release
gi motility
ca2+ signaling
Online Access:https://elifesciences.org/articles/64099

Internet

https://elifesciences.org/articles/64099

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