Decision-tree based model analysis for efficient identification of parameter relations leading to different signaling states.

In systems biology, a mathematical description of signal transduction processes is used to gain a more detailed mechanistic understanding of cellular signaling networks. Such models typically depend on a number of parameters that have different influence on the model behavior. Local sensitivity anal...

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Bibliographic Details
Main Authors: Yvonne Koch, Thomas Wolf, Peter K Sorger, Roland Eils, Benedikt Brors
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24367526/?tool=EBI