A computational diffusion model to study antibody transport within reconstructed tumor microenvironments

Abstract Background Antibodies revolutionized cancer treatment over the past decades. Despite their successfully application, there are still challenges to overcome to improve efficacy, such as the heterogeneous distribution of antibodies within tumors. Tumor microenvironment features, such as the d...

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Bibliographic Details
Main Authors: Ana Luísa Cartaxo, Jaime Almeida, Emilio J. Gualda, Maria Marsal, Pablo Loza-Alvarez, Catarina Brito, Inês A. Isidro
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-020-03854-2