A two-way communication between microglial cells and angiogenic sprouts regulates angiogenesis in aortic ring cultures.

Myeloid cells have been associated with physiological and pathological angiogenesis, but their exact functions in these processes remain poorly defined. Monocyte-derived tissue macrophages of the CNS, or microglial cells, invade the mammalian retina before it becomes vascularized. Recent studies cor...

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Bibliographic Details
Main Authors: Simin F Rymo, Holger Gerhardt, Fredrik Wolfhagen Sand, Richard Lang, Anne Uv, Christer Betsholtz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3018482?pdf=render