Efficient generation of male germ-like cells derived during co-culturing of adipose-derived mesenchymal stem cells with Sertoli cells under retinoic acid and testosterone induction

Efficient generation of male germ-like cells derived during co-culturing of adipose-derived mesenchymal stem cells with Sertoli cells under retinoic acid and testosterone induction

Abstract Background Adipose-derived mesenchymal stem cells (ADMSCs) are considered an efficient and important candidate for male infertility treatment because they contain pluripotent stem cells, which can differentiate into all cells from three germ layers. However, the efficient generation of male...

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Bibliographic Details
Main Authors: Yanxia Luo, Lili Xie, Ali Mohsin, Waqas Ahmed, Chenze Xu, Yan Peng, Haifeng Hang, Yingping Zhuang, Ju Chu, Meijin Guo
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Stem Cell Research & Therapy
Subjects:
Adipose-derived mesenchymal stem cells
Germ cell
Sertoli cell
Signaling pathways
Retinoic acid
Testosterone
Online Access:http://link.springer.com/article/10.1186/s13287-019-1181-5

Internet

http://link.springer.com/article/10.1186/s13287-019-1181-5

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