Human Cognitive Ability Is Modulated by Aromatase Availability in the Brain in a Sex-Specific Manner

Human Cognitive Ability Is Modulated by Aromatase Availability in the Brain in a Sex-Specific Manner

The enzyme aromatase catalyzes the final step in estrogen biosynthesis, converting testosterone to estradiol, and is expressed in the brain of all mammals. Estrogens are thought to be important for maintenance of cognitive function in women, whereas testosterone is thought to modulate cognitive abil...

Full description

Bibliographic Details
Main Authors: Nelly Alia-Klein, Rebecca N. Preston-Campbell, Sung Won Kim, Deborah Pareto, Jean Logan, Gene-Jack Wang, Scott J. Moeller, Joanna S. Fowler, Anat Biegon
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Neuroscience
Subjects:
aromatase
[11C]vorozole
estrogen
testosterone
cognition
PET
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.565668/full

Internet

https://www.frontiersin.org/article/10.3389/fnins.2020.565668/full

Similar Items