Dissecting antibodies with regards to linear and conformational epitopes.

An important issue for the performance and specificity of an antibody is the nature of the binding to its protein target, including if the recognition involves linear or conformational epitopes. Here, we dissect polyclonal sera by creating epitope-specific antibody fractions using a combination of e...

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Bibliographic Details
Main Authors: Björn Forsström, Barbara Bisławska Axnäs, Johan Rockberg, Hanna Danielsson, Anna Bohlin, Mathias Uhlen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4376703?pdf=render