Identification of Blood-Based Biomarkers for the Prediction of the Response to Neoadjuvant Chemoradiation in Rectal Cancer

Identification of Blood-Based Biomarkers for the Prediction of the Response to Neoadjuvant Chemoradiation in Rectal Cancer

The current standard of care for patients with locally advanced rectal cancer (LARC) is neoadjuvant chemoradiation (nCRT) followed by total mesorectal excision surgery. However, the response to nCRT varies among patients and only about 20% of LARC patients achieve a pathologic complete response (pCR...

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Bibliographic Details
Main Authors: Delphine Dayde, Jillian Gunther, Yutaka Hirayama, David C. Weksberg, Adam Boutin, Gargy Parhy, Clemente Aguilar-Bonavides, Hong Wang, Hiroyuki Katayama, Yuichi Abe, Kim-Anh Do, Kazuo Hara, Takashi Kinoshita, Koji Komori, Yasuhiro Shimizu, Masahiro Tajika, Yasumasa Niwa, Y. Alan Wang, Ronald DePinho, Samir Hanash, Sunil Krishnan, Ayumu Taguchi
Format: Article
Language:English
Published: MDPI AG 2021-07-01
Series:Cancers
Subjects:
rectal cancer
neoadjuvant chemoradiation
mouse model
proteomics
biomarkers
Online Access:https://www.mdpi.com/2072-6694/13/14/3642

Internet

https://www.mdpi.com/2072-6694/13/14/3642

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