A novel sialic acid-binding adhesin present in multiple species contributes to the pathogenesis of Infective endocarditis.

A novel sialic acid-binding adhesin present in multiple species contributes to the pathogenesis of Infective endocarditis.

Bacterial binding to platelets is a key step in the development of infective endocarditis (IE). Sialic acid, a common terminal carbohydrate on host glycans, is the major receptor for streptococci on platelets. So far, all defined interactions between streptococci and sialic acid on platelets are med...

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Bibliographic Details
Main Authors: Meztlli O Gaytán, Anirudh K Singh, Shireen A Woodiga, Surina A Patel, Seon-Sook An, Arturo Vera-Ponce de León, Sean McGrath, Anthony R Miller, Jocelyn M Bush, Mark van der Linden, Vincent Magrini, Richard K Wilson, Todd Kitten, Samantha J King
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009222

Internet

https://doi.org/10.1371/journal.ppat.1009222

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