High nitrogen stainless steel drug-eluting stent - Assessment of pharmacokinetics and preclinical safety in vivo

Pharmacokinetic analyses were performed using 20 pigs for 120-days implantation, while one sirolimus-eluting stent was implanted into one of their coronary artery. At different time points, the residual sirolimus on the stent, delivered locally (to artery wall), regionally (to adjacent and downstrea...

Full description

Bibliographic Details
Main Authors: Shanshan Chen, Zhifeng Yao, Yongbiao Guan, Hui Yang, M. Babar Shahzad, Yizhe Wu, Bingchun Zhang, Li Shen, Ke Yang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2020-12-01
Series:Bioactive Materials
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X20300980