Caspase-11 Mediates Pyroptosis of Tubular Epithelial Cells and Septic Acute Kidney Injury

Caspase-11 Mediates Pyroptosis of Tubular Epithelial Cells and Septic Acute Kidney Injury

Background/Aims: Acute kidney injury (AKI) is a serious complication of sepsis and has a high morbidity and mortality rate. Caspase-11 induces pyroptosis, a form of programmed cell death that plays a critical role in endotoxic shock, but its role in tubular epithelial cell death and whether it contr...

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Bibliographic Details
Main Authors: Zhiming Ye, Li Zhang, Ruizhao Li, Wei Dong, Shuangxin Liu, Zhilian Li, Huaban Liang, Lifen Wang, Wei Shi, Asrar B. Malik, Kwong Tai Cheng, Xinling Liang
Format: Article
Language:English
Published: Karger Publishers 2019-06-01
Series:Kidney & Blood Pressure Research
Subjects:
Caspase-11
Pyroptosis
Tubular epithelial cells
Sepsis
Acute kidney Injury
Online Access:https://www.karger.com/Article/FullText/499685

Internet

https://www.karger.com/Article/FullText/499685

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