Mimicking p14ARF phosphorylation influences its ability to restrain cell proliferation.

Mimicking p14ARF phosphorylation influences its ability to restrain cell proliferation.

The INK4a/ARF locus on the short arm of chromosome 9 is one of the most frequently altered loci in human cancer. It is generally accepted that ARF is involved in oncogenic checkpoint pathways by sensitizing incipient cancer cells to undergo growth arrest or apoptosis through both p53-dependent and i...

Full description

Bibliographic Details
Main Authors: Maria Vivo, Michela Ranieri, Federica Sansone, Cristina Santoriello, Raffaele A Calogero, Viola Calabrò, Alessandra Pollice, Girolama La Mantia
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23308265/pdf/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23308265/pdf/?tool=EBI

Similar Items