Genetically matched human iPS cells reveal that propensity for cartilage and bone differentiation differs with clones, not cell type of origin.

BACKGROUND: For regenerative therapy using induced pluripotent stem cell (iPSC) technology, cell type of origin to be reprogrammed should be chosen based on accessibility and reprogramming efficiency. Some studies report that iPSCs exhibited a preference for differentiation into their original cell...

Full description

Bibliographic Details
Main Authors: Akira Nasu, Makoto Ikeya, Takuya Yamamoto, Akira Watanabe, Yonghui Jin, Yoshihisa Matsumoto, Kazuo Hayakawa, Naoki Amano, Shingo Sato, Kenji Osafune, Tomoki Aoyama, Takashi Nakamura, Tomohisa Kato, Junya Toguchida
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3561398?pdf=render