A fast detection of fusion genes from paired-end RNA-seq data

A fast detection of fusion genes from paired-end RNA-seq data

Abstract Background Fusion genes are known to be drivers of many common cancers, so they are potential markers for diagnosis, prognosis or therapy response. The advent of paired-end RNA sequencing enhances our ability to discover fusion genes. While there are available methods, routine analyses of l...

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Bibliographic Details
Main Authors: Trung Nghia Vu, Wenjiang Deng, Quang Thinh Trac, Stefano Calza, Woochang Hwang, Yudi Pawitan
Format: Article
Language:English
Published: BMC 2018-11-01
Series:BMC Genomics
Subjects:
Fusion gene
RNA sequencing
Quasi-mapping
Fusion equivalence class
Online Access:http://link.springer.com/article/10.1186/s12864-018-5156-1

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http://link.springer.com/article/10.1186/s12864-018-5156-1

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