Differential IL-18 Dependence of Canonical and Adaptive NK Cells for Antibody Dependent Responses to P. falciparum

Differential IL-18 Dependence of Canonical and Adaptive NK Cells for Antibody Dependent Responses to P. falciparum

Human adaptive natural killer (NK) cells have diminished reliance on accessory cytokines for their activation whilst being efficiently activated by infected host cells in conjunction with pathogen specific antibodies. Here, we show that potent antibody-dependent NK cell responses are induced by Plas...

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Bibliographic Details
Main Authors: Samuel Sherratt, Avnish Patel, David A. Baker, Eleanor M. Riley, Martin R. Goodier
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Immunology
Subjects:
NK cells
Plasmodium falciparum
IL-18
FcεR1γ
CD57
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.00533/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.00533/full

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