GATA Factor-Mediated Gene Regulation in Human Erythropoiesis

Summary: Erythroid commitment and differentiation are regulated by the coordinated action of a host of transcription factors, including GATA2 and GATA1. Here, we explored GATA-mediated transcriptional regulation through the integrative analysis of gene expression, chromatin modifications, and GATA f...

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Bibliographic Details
Main Authors: Oriana Romano, Luca Petiti, Tristan Felix, Vasco Meneghini, Michel Portafax, Chiara Antoniani, Mario Amendola, Silvio Bicciato, Clelia Peano, Annarita Miccio
Format: Article
Language:English
Published: Elsevier 2020-04-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004220302029